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Background of this research is the globalization and development of science, especially in the field of information and communication technology and communication that has influenced and has implications for changes and renewal of people's lives, including in the field of nursing. So that the role of information and communication in this aspect of life is very important, even the futurists, for the most part, have an agreement that one of the most important strengths as the source of future power is information. Purpose: identify the use of information technology in nursing to determine the effectiveness of the use of information systems in nursing, identify nurses 'knowledge about the effectiveness of nursing information systems, identify nurses' knowledge seen from the socialization of the effectiveness of nursing information systems. Method: Quantitative Research Type with a survey approach conducted on 220 nurses. Significant validity test is <0.05, Cronbach Alpha reliability test> 0.60. The data is then tested in a classic assumption test consisting of multicollinearity tests, autocorrelation tests, heteroscedasticity tests, normality tests, multiple linear regression, t-tests, F tests, coefficient of determination tests. Results: the use of information technology affects the effectiveness of nursing information systems. Nurse knowledge does not affect the effectiveness of nursing information systems. Nurse knowledge seen from socialization does not affect the effectiveness of nursing information systems. The use of information technology and nurse knowledge influences the effectiveness of nursing information systems. The results of the coefficient of determination that affect the use of information technology, knowledge of nurses, socialization as a control variable on the effectiveness of nursing information systems. Suggestion: Hospital managers must pay attention to the quality of nursing human resources, through training, certification, recognition of competencies, supervision, selection, and guidance aimed at improving safe, comfortable and satisfying services for patients, families, communities. Keywords—Information systems; knowledge; nursing; socialization

Socialization of Information Technology Utilization and Knowledge of Information System Effectiveness at Hospital Nurses in Medan, North Sumatra