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formation of the phospholipid and the ion. The association constant for the complex formation of Ca 2+ with the lipid was three orders of magnitude higher than those of monovalent cations with the lipid. The present result suggests that the strong complex formation of highly hydrophilic metal cations with a lipid membrane results in a higher affinity to biomembrane surfaces.

journal of nuclear and radiochemical sciences

Evaluation of the Associate Constant of a Phospholipid - Ca2+ Complex Using a Phospholipid Monolayer Adsorbed at an Aqueous |1, 2-dichloroethane Interface