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Advanced incurable cancer patients receive palliative chemother apy to prolong their life and improve quality of life. However, physicians should assess the timing to discontin ue the treatment, especially near the final months of life, as palliative chemotherapy may accompany considerable toxicity. Even though there are no clear guidelines regarding the withdrawal timing for anticancer treatment in pal liative setting, it is important clarify the issue for quality of care for advanced cancer patients. Here, we present two patients who received palliative chemotherapy for advanced colon cancer and non-small cell lung cancer, respectively. In both cases, it was jointly determined to stop palliative chemotherapy, and best efforts are made to r elieve troublesome symptoms. The cases and upto-date literature review will highlight the importance of the timing of discontinuation of cancer treatments when changes are being made to the health care system and hospice an d palliative medicine is taking root in Korea.

Cases and Literature Review of Timing for Withdrawal of Palliative Chemotherapy