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the gastric ulcer and cancer causing bacteria, helicobacter Pylori have uniquely adapted to swim across the viscoelastic mucus gel that lines the stomach epithelial surface and colonize in the harsh acidic environment of the stomach. in this paper we first briefly review results of bacteria tracking and oscillatory shear rheology studies to suggest how the bacteria get across the viscoelastic mucus gel by using a chemical mechanism to raise the pH from acidic to neutral which also triggers a gel to sol transition of mucin. We then present new microrheology studies to show that the bacterium influences the Brownian motion of spherical tracer particles in culture broth solution and in solutions of gastric mucin. the elastic and viscous moduli obtained by tracking particles in the mucin solutions are found to decrease in the presence of bacteria. We also examined the Brownian motion of the bacteria themselves and find that motile bacteria display super-diffusive anomalous Brownian motion while the immotile bacteria exhibit regular diffusive Brownian motion. keywords: microrheology, particle tracking, bacteria tracking, mucin, h. pylori kulcsszavak: mikroreológia, részecskemozgás, bacterium mozgás, mucin, h. pylori Rama BANSIL rama Bansil is a Professor of Physics and Professor of materials science and engineering at Boston university. she works in the area of soft condensed matter physics and biophysics. Her current research project investigating the motility of the ulcer causing bacterium and its impact on the gelation of mucin is funded by a grant from nsF. Professor Bansil held a junior Faculty Fellowship of the American cancer society and was also a Bunting Fellow at radcliffe college, Harvard university. she is a Fellow of the American Physical society. Joseph hARDCASTLE joseph Hardcastle is a physics Ph. D student at Boston university working under the supervision of Professor rama Bansil. His research focuses on Helicobacter Pylori’s swimming behavior and motility. currently he is exploring how cell morphology influences bacterial motility and their ability to penetrate a mucus layer. in addition to his academic research joseph is active in stem education and outreach. joseph earned his m. s. from Boston university and B. s. from james madison university, usA. Maira Constantino maira constantino is a Physics graduate student at Boston university. she works in experimental biophysics under the supervision of Professor rama Bansil. she is currently investigating the helical trajectory of Helicobacter Pylori and its relationship with the bacterium’s body parameters. maira earned a B.sc. and m.sc. in Physics at universidade estadual de campinas, Brazil.

Microrheology of Mucin: Tracking Particles and Helicobacter Pylori Bacteria