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Dense breast tissue increases the risk of breast cancer [1,2] and can mask breast cancer, thereby resulting in false-negative mammography examinations [3]. Recently, legislation has been passed in many states of the United States that requires direct notification to women of their breast density on screening mammography, and information on supplementary screening tools such as ultrasononography (US) or magnetic resonance imaging (MRI) for women with dense breasts [4]. Thus, after the enactment of this law, the number of supplementary screening US evaluations performed in women with mammographically dense breasts in the United States has increased [5-7]. This review presents the cancer yield and the clinico-pathological characteristics of cancer detected by screening US only, including those found through supplementary hand-held screening US and automated breast ultrasonography (ABUS) in various countries.

Characteristics of breast cancer detected by supplementary screening ultrasonography