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(antithrombin III), C(protein C), S(protein S)     K- (natural anticoagulant)         .      (deep vein thrombosis, DVT)  (pulmonary embolism, PE)   .  C   200-500  1, S  500  1,    2,000-5,000  1  .       50%      .  432    K-   3    4 (glycosylation)   .   α- 4   (oligosaccharide)  .    FIIa FXa  FVIIa, FIXa, FXIa  . ,    2,000-4,000     . C       K- .   C       .  C , , S   FVa FVIIIa     .  S 635    K    C      FVa FVIIIa      .   S  60% C4b- (C4b-binding protein, C4b-BP)    40%      C      ). , C, S          .   , C,  Original Article

clinical and experimental thrombosis and hemostasis

Performance Evaluation of Innovance Antithrombin, Berichrom Protein C and Innovance Free Protein S Assays Using the Automated Coagulation Analyzer Sysmex CS-5100