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With the use of minimally invasive techniques (MIM) treated 489 patients with cystic-colloid nodes. Laser-induced thermotherapy (LITT) — 371 patient, Ethanol destruction of ED — 54 patients, 63 — combined technique (KombiLITT). Dynamics of node size was assessed in 356 patients (72.8%). LITT — 252 patients, ED — 50 patients KombiLITT — 52 patients. LITT used in the treatment of solid structure nodes. Additional nodes up to 1 cm 3 after LITT large part diminished by more than 50% (43 of 76). Additional nodes 1—2 cm 3 also decreased more than half by more than 50% (39 of 67). Among nodules greater than 4 cm 3 was not a single site that would reduce in volume by more than 75%. However, most of them decreased by more than 25%. The algorithm of differential treatment of cystic nodes. ED performed in 54 patients with cystic destruction of a site more than 70%. Marked decrease in the average volume at 4.68 ± 2.25 cm 3 to 1.15 ± 0.9 cm 3 . KombiLITT performed in 63 patients with cystic cavity 20 to 70%. Volume units decreased at 7.98 ± 4.56 cm 3 to 1.87 ± 0.9 cm 3 . LITT performed in 30 patients with major nodes and cystic cavities less than 20% of the site. Marked decrease in the volume of units at 2.89 ± 1.25 cm 3 and 1.42 ± 0.8 cm 3 . LITT held 31 patients with small cystic nodes to 1 cm 3 . Marked decrease in size at 0.69 ± 0.23 cm 3 to 0.29 ± 0.12 cm 3 . It has been shown that changes in thyroid status after MIM operations does not occur.

Four years of experience of minimally invasive treatment of benign thyroid nodule