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Traditionally, these agents produce minor side effects (rash, fever, urticaria) in 5-10% of the treated patients and ma-jor side effects (agranulocytosis, vasculitis, hepatic toxicity) much less frequently. These side effects ap-pear more likely to be dose-related for methimazole (MMI) rather than propylthiouracil (PTU).

Antithyroid drugs used in the treatment of hyperthyroidism during breast feeding. An update and new perspectives