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In modern society, it is reported that overstress has been one of obstacles to human body’s mental and physical health. For instance, so-called lifestyle-related diseases (cancer, hardening of the arteries, hypertension, diabetes, etc.) are mainly caused by active oxygen and free radical formed excessively in body, which induce various diseases that are caused by cell damages because of protein denaturation, lipoperoxidation, nucleolytic degradation and enzyme inactivation. Recently, health-consciousness has been promoted and it is highly accepted that it would be beneficial to take traditional food in which there are active compositions for prevention of disease or for antiaging. Lichen has been utilized for food since the ancient time and is considered to contain its special compositions because of its growth as homobium of fungi and algae. It is also reported that lichen is effective to inhibit lifestyle-related diseases such as hypertension and hypercholesteremia. Physiological Activity of Chinese Lichen (Gyrophora esculenta) Component, Methyl 2,4-Dihydroxy-6-methylbenzoate and the Related Compounds