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Latar Belakang: Terdapat banyak agen topikal yang tersedia untuk perawatan partial thickness burns. Kami menguji Moist Exposed Burn Ointment (MEBO) dan madu sebagai dressings agents; dengan mengetahui sifat-sifat antibakteri, anti in!amasi, dan penyembuhan luka. Agen tersebut juga telah terbukti lebih baik daripada silver sulphadiazine dalam perawatan luka bakar Metode: Total 34 pasien dibagi secara acak ke dalam grup MEBO dan grup madu lokal Indonesia. Dressings diganti setiap harinya, dengan dilakukan intervensi yang sesuai. Kedalaman dan luas luka bakar dinilai pada saat pasien datang ke rumah sakit dan sekali seminggu selama dua minggu. Tingkat nyeri dinilai menggunakan Numeric Rating Scale (NRS). Dilakukan kultur dari swab luka setiap minggunya untuk mengetahui pro"l mikroorganisme. Dilakukan penghitungan biaya perawatan per hari dari setiap grup. Hasil: Pasien dengan acute partial thickness burn pada grup MEBO menunjukkan penyembuhan yang lebih cepat dibandingkan dengan grup madu. Skor NRS untuk nyeri juga lebih rendah pada grup MEBO. MEBO lebih efektif dalam mengurangi kolonisasi bakteri. Biaya perawatan luka dengan MEBO sampai penyembuhan komplit lebih rendah dibanding madu. Kesimpulan: Dalam perawatan partial thickness burns, MEBO lebih superior dibanding dengan madu lokal karena menyebabkan penyembuhan luka lebih cepat, peredaan nyeri yang lebih baik, kolonisasi bakteri yang lebih sedikit, dan penggunaan biaya perawatan yang lebih efektif. Kata Kunci: MEBO,Honey, second degree burns, epithelization, pain scale, bacterial colonization,costeffectiveness Background: Many topical agents are available for the treatment of partial thickness burns. We examined Moist Exposed Burn Ointment (MEBO) and honey as dressing agents; regarding their natural antibacterial, anti-in!ammatory, and wound healing properties. They have also been proven to be superior than silver sulphadiazine in treating burn wound. Methods: A total of 34 patients were randomly allocated into MEBO group and Indonesian local honey group. The dressings are changed daily, with corresponding interventions applied. The depth and extent of burn wounds were assessed upon patient’s admission and once a week for two weeks. Pain level was evaluated using the Numeric Rating Scale (NRS). The wound swabs were cultured weekly to obtain microorganisms pro"le. The cost-per-day of each group were counted. Result: Acute partial thickness burn in MEBO group showed faster healing compared to honey group. NRS scores for pain were also lower in MEBO group. MEBO was found to be more effective in decreasing bacterial colonization. Cost of treating wound using MEBO until complete healing was also lesser than local honey. Conclusions: As topical agent to treat partial thickness burns, MEBO is superior compared to local honey due to faster healing, better pain relief, fewer bacterial colonization and the more cost-effective usage.

Randomized Control Trial Comparing Moist Exposed Burn Ointment and Honey as Dressings Agents in Patients with Second -Degree Burns