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Background The aim of this study is to figure out the clinicopathologic factors of invasive ductal carcinoma affecting to actual 5-year survival rate(5-YSR). Patients and Methods From Jan of 1999 to Dec of 2003, a total of 365 female patients with invasive ductal carcinoma who undergone operations in Pusan National University Hospital were enrolled for this study. The univariate and multivariate analysis were performed with clinicopathologic factors and actual 5-YSR. Results The mean age of patients was 47.6 years and mean follow-up period was 62.8 months. Thirty-nine of the 365 patients had expired within 5 years after operation and the actual 5-YSR was 89.3%. The variables affecting to actual 5-YSR of breast cancer in univariate analysis were preoperative CA 15-3 level(p=0.0211), tumor size(p lymphovascular(p=0.0004) and perineural invasion(p=0.0192) of primary tumor, positivity of progesterone receptor(p=0.0457) and HER2-neu gene(p=0.0179), breast-conserving surgery(p transfusion(p=0.0002), neoadjuvant and adjuvant chemotherapy(p But, in multivariate analysis, significant factors with actual 5-YSR were only pathologic tumor stage(p=0.0012) and adjuvant chemotherapy(p=0.0102). Conclusion The pathologic tumor stage and adjuvant chemotherapy were related with actual 5-YSR of invasive ductal carcinoma significantly. The adjuvant chemotherapy should be selected carefully with considering clinicopathologic factors of breast cancer, because various combinations are possible even if the pathologic tumor stage is difficult to change by physician.

Clinocopathologic Factors Affecting Actual 5-year Survival Rate of Invasive Ductal Carcinoma: a Single-center Analysis of 365 Patients