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In present year 2019, 25 years of the premiere of the film Philadelhia by Jonathan Demme have been fulfilled, which in our country took place in March 1994. With this paper, we try to make a reflection of the changes that have occurred in HIV infection in diagnosis, treatment and prognosis as well as in the social field: when the film was presented about 10 years later first patients were diagnosed, HIV infection was considered as a disease with widespread social rejection with stigmatization of several risk groups (homosexuals, intravenous drug users and hemophiliacs) and ways of transmission, diagnosis was usually made in late stages of the disease with severe immunodeficiency symptoms such as Kaposi’s sarcoma, Pneumocystis carinii pneumonia, cerebral toxoplasmosis and cryptococcal meningitis and the treatments were ineffective. At present, diagnosis and treatment is much earlier and more effective and social stigmatization has disappeared.

25 años después del estreno de Philadelphia (1993), ¿Qué cosas han cambiado en la infección por VIH?