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We search for new charmless decays of neutral $b$--hadrons to pairs ofcharged hadrons with the upgraded Collider Detector at the Fermilab Tevatron.Using a data sample corresponding to 1 fb$^{-1}$ of integrated luminosity, wereport the first observation of the \BsKpi decay, with a significance of$8.2\sigma$, and measure $\BR(\BsKpi) = (5.0 \pm 0.7\stat \pm 0.8\syst)\times10^{-6}$. We also report the first observation of charmless $b$--baryon decaysin the channels \Lbppi and \LbpK with significances of $6.0\sigma$ and$11.5\sigma$ respectively, and we measure $\BR(\Lbppi) = (3.5 \pm 0.6\stat \pm0.9\syst)\times 10^{-6}$ and $\BR(\LbpK) = (5.6 \pm 0.8\stat \pm1.5\syst)\times 10^{-6}$. No evidence is found for the decays \BdKK and\Bspipi, and we set an improved upper limit $\BR(\Bspipi) < 1.2\times 10^{-6}$at the 90% confidence level. All quoted branching fractions are measured using$\BR(\BdKpi)$ as a reference.

Observation of New Charmless Decays of Bottom Hadrons