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Spemann proposed that the development of the visual system requires inductive events between the optic vesicle and the overlying ectoderm. More recent evidence suggests that lens formation involves a multi-step process including competence, bias and final determination. Several genes have been discovered that are expressed in a spatial and temporal manner during these stages and consequently may be considered candidates for controlling at least some of these complicated processes.

Molecular analysis of the development of the vertebrate visual system.