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The response of cells to a wide variety of stresses has been known to induce the synthesis of families of proteins known as the heat shock proteins (Hsps). Although first considered as special proteins that had cytoprotective properties under stress conditions, Hsps were subsequently found to play important roles in basic cellular processes such as protein folding and intracellular protein transport. The findings that Hsps were involved in disease processes provoked an increased interest in the study of the stress response in many cell models from bacteria to humans. Thus, if one looks for Hsps in the NCBI database, one is confronted with an astonishing 20 657 entries (15 July 2004), enough to discourage any newcomers to the field. As the knowledge gap between the “western societies” and the developing countries with respect to this fascinating field widened, Professors S.C. Lakhotia (Varanasi, India) and W. Schumann (Bayreuth, Germany) organized a first workshop on the “Molecular Biology of Stress Responses” at Banaras University in Varanasi, India, in October 1997. The meeting aimed at permitting young scientists from developing countries to participate in the rapidly developing field of the basic aspects of the stress responses and its potential for applications to medical, agricultural, and environmental problems (Csermely and Lakhotia 1998). Given the enthusiasm of the young (and old) participants, a second workshop was organized in Wuhan, China, in 1999 (organizer Tangchun Wu) and in Mendoza, Argentina, in 2001 (organizer D. Ciocca) (reviewed by Grover 2002).  The Cell Stress Society International sponsored the Fourth International Workshop on the Molecular Biology of Stress Responses held in Wuhan and Yichang, China, on 13–16 May 2004. The workshop organized by Professors Tangchun Wu (Tongji Medical College), Lawrence E. Hightower (University of Connecticut), and Robert M. Tanguay (Universite Laval) attracted around 100 scientists mainly from different regions of China and also from Canada, Denmark, France, Germany, The Netherlands, Russia, Sweden, the United Kingdom, and the United States. Many of the international scientists participating in the workshop arrived a day or two before the meeting and were treated to tours of the Yellow Crane Tower and the Hubei Provincial Museum in Wuhan.

Stress under the dam: meeting report of the Fourth International Workshop on the Molecular Biology of Stress Responses