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A 61-year-old man was being assessed for multiple sclerosis. His paired cerebrospinal fluid (CSF) and serum samples were sent to the clinical biochemistry laboratory for oligoclonal band analysis by CSF isoelectric focusing and IgG immunofixation (Fig. 1). Creutzfeldt–Jakob disease immunoassay panel with CSF 14-3-3, tau, and S100B proteins was negative.Fig. 1. Isoelectric focusing and IgG immunofixation of the patient's samples. Lane 1, …

Multiple Cerebrospinal Fluid Bands with Accompanying Serum Bands