Marked Biological Variance in Endocrine and Biochemical Markers in Childhood: Establishment of Pediatric Reference Intervals Using Healthy Community Children from the CALIPER Cohort
Author(s) -
Dana Bailey,
David Colantonio,
Lianna Kyriakopoulou,
A Cohen,
Man Khun Chan,
David Armbruster,
Khosrow Adeli
Publication year - 2013
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2013.204222
Subject(s) - medicine , cohort , percentile , vitamin d and neurology , body mass index , pediatrics , endocrinology , physiology , statistics , mathematics
Reference intervals are indispensable in evaluating laboratory test results; however, appropriately partitioned pediatric reference values are not readily available. The Canadian Laboratory Initiative for Pediatric Reference Intervals (CALIPER) program is aimed at establishing the influence of age, sex, ethnicity, and body mass index on biochemical markers and developing a comprehensive database of pediatric reference intervals using an a posteriori approach.
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