Open AccessSerum Soluble CD163 Predicts Risk of Type 2 Diabetes in the General Population
Author(s) -
Holger Jon Møller,
Ruth FrikkeSchmidt,
Søren K. Moestrup,
Børge G. Nordestgaard,
Anne TybjærgHansen
Publication year - 2010
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2010.154724
Subject(s) - type 2 diabetes , population , diabetes mellitus , medicine , endocrinology , environmental health
Activation of adipose tissue macrophages with concomitant low-grade inflammation is believed to play a central role in the development of type 2 diabetes. We tested whether a new macrophage-derived biomarker, soluble CD163 (sCD163), identifies at-risk individuals before overt disease has developed.
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