Liquid Chromatography–Tandem Mass Spectrometry Assay for Androstenedione, Dehydroepiandrosterone, and Testosterone with Pediatric and Adult Reference Intervals
Author(s) -
Mark M. Kushnir,
Takara L. Blamires,
Alan L. Rockwood,
William L. Roberts,
Bingfang Yue,
Evrim Erdogan,
Ashley M. Bunker,
A.W. Meikle
Publication year - 2010
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2010.143222
Subject(s) - androstenedione , dehydroepiandrosterone , testosterone (patch) , endocrinology , medicine , chemistry , androgen , chromatography , hormone
Measurement of serum androgens is important in adult, geriatric, pediatric endocrinology, and oncology patients. We developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay for simultaneous measurement of androstenedione, dehydroepiandrosterone (DHEA), and testosterone in these patients.
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