Open AccessPlasma MicroRNAs as Sensitive and Specific Biomarkers of Tissue Injury
Author(s) -
Omar Laterza,
Lee P. Lim,
Philip W. Garrett-Engele,
Kateřina Vlasáková,
Nagaraja Muniappa,
Wesley Tanaka,
Jason M. Johnson,
Joseph F. Sina,
Thomas L. Fare,
Frank D. Sistare,
Warren E. Glaab
Publication year - 2009
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2009.131797
Subject(s) - microrna , toxicity , liver injury , biology , muscle tissue , liver tissue , endogeny , brain tissue , blood plasma , pathology , medicine , endocrinology , gene , biochemistry
MicroRNAs (miRNAs) are endogenous, small noncoding RNAs. Because of their size, abundance, tissue specificity, and relative stability in plasma, miRNAs hold promise as unique accessible biomarkers to monitor tissue injury.
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