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Anopheles cracens  has been incriminated as the vector of human knowlesi malaria in peninsular Malaysia. Besides, it is a good laboratory vector of  Plasmodium falciparum  and  P .  vivax . The distribution of  An .  cracens  overlaps with that of  An .  maculatus , the human malaria vector in peninsular Malaysia that seems to be refractory to  P .  knowlesi  infection in natural settings. Whole genome sequencing was performed on  An .  cracens  and  An .  maculatus  collected here. The draft genome of  An .  cracens  was 395 Mb in size whereas the size of  An .  maculatus  draft genome was 499 Mb. Comparison with the published Malaysian  An .  maculatus  genome suggested the  An .  maculatus  specimen used in this study as a different geographical race. Comparative analyses highlighted the similarities and differences between  An .  cracens  and  An .  maculatus , providing new insights into their biological behavior and characteristics.

Draft Genomes of Anopheles cracens and Anopheles maculatus: Comparison of Simian Malaria and Human Malaria Vectors in Peninsular Malaysia