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Objective  To compare the effectiveness of a physiotherapy programme with a control treatment of advice and education in patients with neurogenic claudication symptoms.    Design  Pragmatic randomised controlled clinical trial.    Setting  Primary care-based musculoskeletal service.    Patients  Adults aged 50 or over with neurogenic claudication symptoms causing limitation of walking.    Interventions  Condition-specific home exercises combined with advice and education, or advice and education alone.    Main outcome measures  The primary outcome was the difference in improvement of symptom severity scores on the Swiss Spinal Stenosis Scale at eight weeks. Secondary outcomes included measures of physical function, pain and general well-being at eight weeks and 12 months.    Results  There was no significant difference between groups in the Swiss Spinal Stenosis symptom severity scale at eight weeks (t = 0.47, p = 0.643): mean change (SD) control group −0.18 (0.47), treatment group −0.10 (0.66), difference (95% CI) 0.08 (−0.19, 0.35); baseline-adjusted difference 0.06 (−0.19, 0.31)]. An unplanned subgroup analysis suggested that for patients with the top 25% of baseline symptom severity scores, the physiotherapy exercise programme resulted in an improvement in the primary outcome, and modest but consistently better secondary outcomes at both time-points compared to the control group. The effectiveness in different subgroups requires further direct evaluation.    Conclusions  In the treatment of patients with neurogenic claudication symptoms, a physiotherapist-prescribed home exercise programme is no more effective than advice and education.    Ethical approval  The study was approved by  Leeds Central Ethics Committee and informed consent was given by all participating patients.Copyright  The Corresponding Author has the right to grant on behalf of all authors and does grant on behalf of all authors, a worldwide licence to the Publishers and its licensees in perpetuity, in all forms, formats and media (whether known now or created in the future), to i) publish, reproduce, distribute, display and store the Contribution, ii) translate the Contribution into other languages, create adaptations, reprints, include within collections and create summaries, extracts and/or, abstracts of the Contribution, iii) create any other derivative work(s) based on the Contribution, iv) to exploit all subsidiary rights in the Contribution, v) the inclusion of electronic links from the Contribution to third party material where-ever it may be located; and, vi) licence any third party to do any or all of the above.    Trial registration    ISRCTN 78288224 – doi10.1186/ISRCTN35836727 ;  UKCRN 4814 .

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A Home Exercise Programme Is No More Beneficial than Advice and Education for People with Neurogenic Claudication: Results from a Randomised Controlled Trial