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U12 intron-specific spliceosomes contain U11 and U12 small nuclear ribonucleoproteins and mediate the removal of U12 introns from precursor-mRNAs. Among the several proteins unique to the U12-type spliceosomes, an  Arabidopsis thaliana  AtU11/U12-31K protein has been shown to be indispensible for proper U12 intron splicing and for normal growth and development of  Arabidopsis  plants. Here, we assessed the functional roles of the rice ( Oryza sativa ) OsU11/U12-31K protein in U12 intron splicing and development of plants. The  U11/U12-31K  transcripts were abundantly expressed in the shoot apical meristems (SAMs) of  Arabidopsis  and rice. Ectopic expression of OsU11/U12-31K in AtU11/U12-31K-defecient  Arabidopsis  mutant complemented the incorrect U12 intron splicing and abnormal development phenotypes of the  Arabidopsis  mutant plants. Impaired cell division activity in the SAMs and inflorescence stems observed in the AtU11/U12-31K-deficient mutant was completely recovered to normal by the expression of OsU11/U12-31K. Similar to  Arabidopsis  AtU11/U12-31K, rice OsU11/U12-31K was determined to harbor RNA chaperone activity. Collectively, the present findings provide evidence for the emerging idea that the U11/U12-31K protein is an indispensible RNA chaperone that functions in U12 intron splicing and is necessary for normal development of monocotyledonous plants as well as dicotyledonous plants.

The Minor Spliceosomal Protein U11/U12-31K Is an RNA Chaperone Crucial for U12 Intron Splicing and the Development of Dicot and Monocot Plants