English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Bacillus thuringiensis  is an important entomopathogenic bacterium belongs to the  Bacillus cereus  group, which also includes  B. anthracis  and  B. cereus . Several genomes of phages originating from this group had been sequenced, but no genome of  Siphoviridae  phage from  B. thuringiensis  has been reported. We recently sequenced and analyzed the genome of a novel phage, BtCS33, from a  B. thuringiensis  strain, subsp.  kurstaki  CS33, and compared the gneome of this phage to other phages of the  B. cereus  group. BtCS33 was the first  Siphoviridae  phage among the sequenced  B. thuringiensis  phages. It produced small, turbid plaques on bacterial plates and had a narrow host range. BtCS33 possessed a linear, double-stranded DNA genome of 41,992 bp with 57 putative open reading frames (ORFs). It had a typical genome structure consisting of three modules: the “late” region, the “lysogeny-lysis” region and the “early” region. BtCS33 exhibited high similarity with several phages,  B. cereus  phage Wβ and some variants of Wβ, in genome organization and the amino acid sequences of structural proteins. There were two ORFs, ORF22 and ORF35, in the genome of BtCS33 that were also found in the genomes of  B. cereus  phage Wβ and may be involved in regulating sporulation of the host cell. Based on these observations and analysis of phylogenetic trees, we deduced that  B. thuringiensis  phage BtCS33 and  B. cereus  phage Wβ may have a common distant ancestor.

Genome Characteristics of a Novel Phage from Bacillus thuringiensis Showing High Similarity with Phage from Bacillus cereus