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MRSA CC130 containing the  mec A homologue  mec A LGA251  were reported from the UK and from Denmark so far from cattle and humans. Here we report on 11 MRSA CC130 among a sample of 12691 isolates of human origin collected from January 2006 until June 2011. MRSA CC130 grew insufficiently on chromogernic agar plates for detection of MRSA; the agglutination test for presence of PBP2a was negative. We designed primers for specific detection of  mec A LGA251  as well as for concomitant detection of both,  mec   LGA251  and  mec A. As already described, the isolates exhibited  spa -types t843, t1736, and t1773. The  ccr A homologue indicated the presence SCC mec   XI . When subjected to further characterization by means of a commercially available microarray the isolates were negative for  sak chp , and  scn , and as expected positive for  hla , untruncated  hlb , and  hld . They furthermore contained  edin B,  aur ,  slp A,  slp B,  slp E. From genes coding for surface and cell wall associated products the  ica -operon,  cap 8,  clf A,  clf F,  ebp S,  fnb A,  fnb B,  sdr C were detected but not  cna . The isolates were negative for enterotoxin genes and  tst , as well as for  eta , and  etb ;  agr -type was III.

Rare Occurrence of Methicillin-Resistant Staphylococcus aureus CC130 with a Novel mecA Homologue in Humans in Germany