English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

The identification of the Tick Borne Relapsing Fever (TBRF) agent in Israel and the Palestinian Authority relies on the morphology and the association of  Borrelia persica  with its vector  Ornithodoros tholozani . Molecular based data on  B. persica  are very scarce as the organism is still non-cultivable. In this study, we were able to sequence three complete 16S rRNA genes, 12 partial  fla B genes, 18 partial  glp Q genes, 16  rrs-ile T intergenic spacers (IGS) from nine ticks and ten human blood samples originating from the West Bank and Israel. In one sample we sequenced 7231 contiguous base pairs that covered completely the region from the 5′end of the 16S rRNA gene to the 5′end of the 23S rRNA gene comprising the whole 16S rRNA ( rrs ), and the following genes: Ala tRNA ( ala T), Ile tRNA  (ile T), adenylosuccinate lyase  (pur B), adenylosuccinate synthetase ( pur A), methylpurine-DNA glycosylase ( mag ), hypoxanthine-guanine phosphoribosyltransferase ( hp t), an hydrolase (HAD superfamily) and a 135 bp 5′ fragment of the 23S rRNA ( rrl A) genes. Phylogenic sequence analysis defined all the  Borrelia  isolates from  O. tholozani  and from human TBRF cases in Israel and the West Bank as  B. persica  that clustered between the African and the New World TBRF species. Gene organization of the intergenic spacer between the 16S rRNA and the 23S rRNA was similar to that of other TBRF  Borrelia  species and different from the Lyme disease  Borrelia  species. Variants of  B. persica  were found among the different genes of the different isolates even in the same sampling area.

Molecular Characterization of Borrelia persica, the Agent of Tick Borne Relapsing Fever in Israel and the Palestinian Authority