Open AccessAlpha-Adducin Gly460Trp Polymorphism and Hypertension Risk: A Meta-Analysis of 22 Studies Including 14303 Cases and 15961 Controls
Author(s) -
Kuo Liu,
Jielin Liu,
Yan Huang,
Ya Liu,
Yuqing Lou,
Zuoguang Wang,
Hong Zhang,
Shan Yan,
Zhizhong Li,
Shaojun Wen
Publication year - 2010
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0013057
Subject(s) - meta analysis , genetic model , allele , medicine , medline , polymorphism (computer science) , publication bias , study heterogeneity , bioinformatics , random effects model , genetic association , genetics , genotype , biology , single nucleotide polymorphism , gene , biochemistry
No clear consensus has been reached on the alpha-adducin polymorphism (Gly460Trp) and essential hypertension risk. We performed a meta-analysis in an effort to systematically summarize the possible association.
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