Open AccessSpermatogonial Stem Cell Niche and Spermatogonial Stem Cell Transplantation in Zebrafish
Author(s) -
Rafael Henrique Nóbrega,
Caaj Douwe Greebe,
Henk van de Kant,
Jan Bogerd,
Luiz R. França,
Rüdiger Schulz
Publication year - 2010
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0012808
Subject(s) - zebrafish , biology , stem cell , microbiology and biotechnology , transplantation , niche , germ cell , cell type , cell , immunology , genetics , medicine , gene , ecology
Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis, and reside within a specific microenvironment in the testes called "niche" which regulates stem cell properties, such as, self-renewal, pluripotency, quiescence and their ability to differentiate.
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