Open AccessPolyADP-Ribosylation Is Required for Pronuclear Fusion during Postfertilization in Mice
Author(s) -
Tomoharu Osada,
Hideki Ogino,
Toshiaki Hino,
Sachiyo Ichinose,
Kenji Nakamura,
Akira Omori,
Toshiaki Noce,
Mitsuko Masutani
Publication year - 2010
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0012526
Subject(s) - pronucleus , microbiology and biotechnology , oocyte activation , biology , chromatin , maturation promoting factor , lamin , metaphase , embryo , oocyte , zygote , cell cycle , genetics , embryogenesis , cell , cyclin dependent kinase 1 , chromosome , gene , nucleus
During fertilization, pronuclear envelope breakdown (PNEB) is followed by the mingling of male and female genomes. Dynamic chromatin and protein rearrangements require posttranslational modification (PTM) for the postfertilization development.
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