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https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

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The case-fatality rate of yellow fever virus (YFV) is one of the highest among arthropod-borne viruses (arboviruses). Although historically, the Asia-Pacific region has remained free of YFV, the risk of introduction has never been higher due to the increasing influx of people from endemic regions and the recent outbreaks in Africa and South America. Singapore is a global hub for trade and tourism and therefore at high risk for YFV introduction. Effective control of the main domestic mosquito vector  Aedes aegypti  in Singapore has failed to prevent re-emergence of dengue, chikungunya and Zika viruses in the last two decades, raising suspicions that peridomestic mosquito species untargeted by domestic vector control measures may contribute to arbovirus transmission. Here, we provide empirical evidence that the peridomestic mosquito  Aedes malayensis  found in Singapore can transmit YFV. Our laboratory mosquito colony recently derived from wild  Ae .  malayensis  in Singapore was experimentally competent for YFV to a similar level as  Ae .  aegypti  controls. In addition, we captured  Ae .  malayensis  females in one human-baited trap during three days of collection, providing preliminary evidence that host-vector contact may occur in field conditions. Finally, we detected  Ae .  malayensis  eggs in traps deployed in high-rise building areas of Singapore. We conclude that  Ae .  malayensis  is a competent vector of YFV and re-emphasize that vector control methods should be extended to target peridomestic vector species.

A peridomestic Aedes malayensis population in Singapore can transmit yellow fever virus