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The World Health Organization (WHO) has recently announced its plan to eliminate Human African trypanosomiasis (HAT). The plan's main focus is on the Trypanosoma brucei gambiense subspecies, which causes 97% of cases [1]. However, total elimination from certain areas has proved extremely difficult previously; there has been ongoing parasite detection in several foci in West Africa, despite effective screening programmes. This has focussed interest on the potential role of asymptomatic human carriers in contributing to transmission. In this report, we present a unique case of a patient harbouring the parasite for more than three decades before developing stage 2 sleeping sickness [2].

plos neglected tropical diseases

Human African Trypanosomiasis Presenting at Least 29 Years after Infection—What Can This Teach Us about the Pathogenesis and Control of This Neglected Tropical Disease?