Open AccessThe Effect of Elevated Body Mass Index on Ischemic Heart Disease Risk: Causal Estimates from a Mendelian Randomisation Approach
Author(s) -
Børge G. Nordestgaard,
Tom Palmer,
Marianne Benn,
Jeppe Zacho,
Anne TybjærgHansen,
George Davey Smith,
Nicholas J. Timpson
Publication year - 2012
Publication title -
plos medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.847
H-Index - 228
eISSN - 1549-1676
pISSN - 1549-1277
DOI - 10.1371/journal.pmed.1001212
Subject(s) - mendelian randomization , body mass index , medicine , disease , cardiology , demography , genetics , biology , genotype , gene , sociology , genetic variants
A Mendelian randomization analysis conducted by Børge G. Nordestgaard and colleagues using data from observational studies supports a causal relationship between body mass index and risk for ischemic heart disease.
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