English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The Actinomycetales bacteria  Rhodococcus opacus  PD630 and  Rhodococcus jostii  RHA1 bioconvert a diverse range of organic substrates through lipid biosynthesis into large quantities of energy-rich triacylglycerols (TAGs). To describe the genetic basis of the  Rhodococcus  oleaginous metabolism, we sequenced and performed comparative analysis of the 9.27 Mb  R. opacus  PD630 genome. Metabolic-reconstruction assigned 2017 enzymatic reactions to the 8632  R. opacus  PD630 genes we identified. Of these, 261 genes were implicated in the  R. opacus  PD630 TAGs cycle by metabolic reconstruction and gene family analysis.  Rhodococcus  synthesizes uncommon straight-chain odd-carbon fatty acids in high abundance and stores them as TAGs. We have identified these to be pentadecanoic, heptadecanoic, and cis-heptadecenoic acids. To identify bioconversion pathways, we screened  R. opacus  PD630,  R. jostii  RHA1,  Ralstonia eutropha  H16, and  C. glutamicum  13032 for growth on 190 compounds. The results of the catabolic screen, phylogenetic analysis of the TAGs cycle enzymes, and metabolic product characterizations were integrated into a working model of prokaryotic oleaginy.

Comparative and Functional Genomics of Rhodococcus opacus PD630 for Biofuels Development