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Table 4. Selection of actively maintained AS databases. Most databases have been constructed from automated large-scale comparisons of transcript sequences to genomic DNA of known genes, following ENSEMBL, UNIGENE, SWISS-PROT annotation and nomenclature, whereas “hybrid-like” approaches attempt to curate AS data by searches of published research. Databases are purposefully different and serve different users needs: they do so in the scope of interrogated genomes and sequence data, splicing conservation, annotation of functional elements, data download, and several other features (last column). They show further differences in their inference of AS events, for reasons such as different primary data, rules to detect splice patterns, and filter criteria.

Strategies for Identifying RNA Splicing Regulatory Motifs and Predicting Alternative Splicing Events