A Conserved Role for Human Nup98 in Altering Chromatin Structure and Promoting Epigenetic Transcriptional Memory | Zendy

William H. Light | Zendy; Jonathan E. Freaney | Zendy; Varun Sood | Zendy; Abbey Thompson | Zendy; Agustina D’Urso | Zendy; Curt M. Horvath | Zendy; Jason H. Brickner | Zendy

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A Conserved Role for Human Nup98 in Altering Chromatin Structure and Promoting Epigenetic Transcriptional Memory

Author(s) -

William H. Light,

Jonathan E. Freaney,

Varun Sood,

Abbey Thompson,

Agustina D’Urso,

Curt M. Horvath,

Jason H. Brickner

Publication year - 2013

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1001524

Subject(s) - biology , chromatin , promoter , rna polymerase ii , epigenetics , transcriptional regulation , transcription (linguistics) , microbiology and biotechnology , genetics , gene , nucleoplasm , transcription factor , gene expression , nucleolus , cytoplasm , linguistics , philosophy

In yeast and humans, interaction of a nuclear pore protein with promoters alters chromatin structure and allows RNA polymerase II to bind, poising them for faster reactivation for several generations.

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