Open AccessWhole Genome Sequence Analysis of Salmonella Enteritidis PT4 Outbreaks from a National Reference Laboratory’s Viewpoint
Author(s) -
Véronique Wuyts,
Sarah Denayer,
Nancy H. C. Roosens,
Wesley Mattheus,
Sophie Bertrand,
Kathleen Marchal,
Katelijne Dierick,
Sigrid C. J. De Keersmaecker
Publication year - 2015
Publication title -
plos currents
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.282
H-Index - 49
ISSN - 2157-3999
DOI - 10.1371/currents.outbreaks.aa5372d90826e6cb0136ff66bb7a62fc
Subject(s) - multiple loci vntr analysis , outbreak , salmonella enteritidis , whole genome sequencing , biodefense , serotype , phage typing , salmonella enterica , biology , salmonella , virology , genome , microbiology and biotechnology , genetics , tandem repeat , gene , bacteria
In April and May 2014, two suspected egg-related outbreaks of Salmonella enterica subsp. enterica serovar Enteritidis (S. Enteritidis) were investigated by the Belgian National Reference Laboratory of Foodborne Outbreaks. Both the suspected food and human isolates being available, and this for both outbreaks, made these the ideal case study for a retrospective whole genome sequencing (WGS) analysis with the goal to investigate the feasibility of this technology for outbreak investigation by a National Reference Laboratory or National Reference Centre without thorough bioinformatics expertise.
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