Open AccessIs There an Association of Physical Activity with Brain Volume, Behavior, and Day-to-day Functioning? A Cross Sectional Design in Prodromal and Early Huntington Disease
Author(s) -
McKenzie Wallace,
Nancy R. Downing,
Spencer Lourens,
James A. Mills,
JiIn Kim,
Jeffrey D. Long,
Jane S. Paulsen,
PREDICT-HD Investigators and Coordinators of the Huntington Study Group
Publication year - 2016
Publication title -
plos currents
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.282
H-Index - 49
ISSN - 2157-3999
DOI - 10.1371/currents.hd.cba6ea74972cf8412a73ce52eb018c1e
Subject(s) - huntington's disease , cross sectional study , association (psychology) , medicine , physical activity , disease , gerontology , psychology , physical medicine and rehabilitation , pathology , psychotherapist
Huntington disease (HD) is a genetic neurodegenerative disease leading to progressive motor, cognitive, and behavioral decline. Subtle changes in these domains are detectable up to 15 years before a definitive motor diagnosis is made. This period, called prodromal HD, provides an opportunity to examine lifestyle behaviors that may impact disease progression.
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