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We have investigated the possibility of using diffuse reflectance polarimetry to detect changes caused by different molecular compounds and concentrations in tissue-simulating phantoms. The effects of glucose, B-alanine and l-lysine at different concentrations in turbid media have been investigated separately. This approach is based on the effect of optical properties on the polarization state of light. The results show that this method has potential for determining changes in molecular concentrations in highly scattering biological media from polarization images.

Effect of molecular concentrations in tissu-simulating phantoms on images obtained using diffuse reflectance polarimetry