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A novel method to detect different sizes of micro-particles using a fiber Bragg grating Fabry-Pérot (FBG-FP) flow cytometer is presented. The chip is composed of a FBG-FP cavity integrated in a microfluidic channel. Solution with three different sizes of polystyrene particles flowing through the channel induces variations in the transmission spectrum of the FBG-FP cavity. Theoretical and experimental data show that different sizes of particles reveal different resonant wavelengths with a good resonance shift sensitivity of 10 -5 . Additionally, the chip is easy to fabricate and features with non-contact and label-free operation. This study demonstrates a promising potential of the FBG-FP flow cytometer in medical and biological sensing.

Continuous detection of micro-particles by fiber Bragg grating Fabry-Pérot flow cytometer