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Rigid endoscopes like graded-index (GRIN) lenses are known tools inbiological imaging, but it is conceptually difficult to miniaturize them. Inthis letter, we demonstrate an ultra-thin rigid endoscope with a diameter ofonly 125 microns. In addition, we identify a domain where two-photon endoscopicimaging with fs-pulse excitation is possible. We validate the ultra-thin rigidendoscope consisting of a few cm of graded-index multi-mode fiber by using itto acquire optically sectioned two-photon fluorescence endoscopic images ofthree-dimensional samples.

Ultra-thin rigid endoscope: Two-photon imaging through a graded-index multi-mode fiber