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The interaction of an organism and its environment is determined, to a significant degree, by the composition of the environment and the biochemical individuality of the given organism. A characteristic of the living organism is to carry the foreign compounds which enter them through continuous cycles of activity like their own constituents. Some of the compounds of the environment accumulate to some extent in the animal body. This storage constitutes a dynamic process. At a certain storage level, effects on the metabolism of normal constituents of the animal body, on the genetical make-up, and on its defence mechanisms (detoxication processes, neuro-endocrine, and immunologic processes) are observed. This paper reports on the size of Organochlorine Insecticides and Poly-chlorinated Biphenyls storage in the human general population in the seventies and some of the biological effects of these compounds on humans and experimental animals.

Organochlorine compounds in the general population of the seventies and some of their biological effects (in man and animals