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Diabetes is believed to affect the hypothalamo-pituitary thyroid axis as well as the peripheral conversion of tetraiodo to triiodothyronine. Thyroid hormones; namely Triiodothyronine (FT3) and Tetraiodothyronine (FT4) are considered as insulin antagonists which potentiate insulin action indirectly. Low thyroid hormones in diabetic patients may be explained by the decreased production of thyrotropin releasing hormone [6,7].

New Reference Values for Thyrotropin Hormone in Diabetic Patients