English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Another possible explanation for the connection of galanin expression and addiction is the interaction between its expression and dopaminergic transmission. In 1987, Norwegian scientists found galanin and dopamine to coexist in nerve endings, for example in the median eminence of hypothalamus [13]. In vitro experiments revealed that galanin inhibited the release of dopamine in a dose-dependent manner, possibly via a presynaptic receptor [14]. Furthermore, preclinical research results could show that while dopamine transmission is inhibited, galanin and the synthetic galanin receptor agonist gal none reduced cocaine-induced hyperactivity and relapse-like behavior [15]. Also, Picciotto mentioned hypothalamic function to modulate the mesolimbic dopamine system and named galanin receptors to be potential targets for the development of novel treatments for addiction [16].

Low Galanin Serum Levels are Associated with Anxiety in Opioid-Maintained Patients