English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The endothelium plays a pivotal role in the regulation of homeostasis through expression of the antithrombotic and prothrombotic factor. Transdifferentiation requires lesser cell subcultures and can reduce the chance of alterations. We describe in the current article the transdifferentiation of blood mononucleated cells to committed progenitor endothelial cells. Materials and methods Experiments were set up for mononucleated cells culture, transdifferentiation of mononucleated cells to committed progenitor endothelial cells, characterization of mononucleated cells to committed progenitor endothelial cells to terminal transdifferentiated endothelial cells. Results It was confirmed that 10 weeks of maintenance of mononucleated cells in culture with supplementation of vascular endothelial growth factor in endothelial conditioning growth medium brings about mononucleated cells to terminal transdifferentiation of endothelial cells, which was confirmed finally by cell characterization (immunocytochemistry) using the specific marker vWF+. Conclusion Vascular endothelial growth factor has the potential signalling cascade that can transdifferentiate mononucleated cells to endothelial cells in culture.

oa stem cells

Peripheral venous blood mononucleated cells have potential to commit to progenitor endothelial cells when exposed to vascular endothelial growth factor