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Introduction Why do we need neuro-scientific psychiatry, how can we achieve it, and when will we know it has been achieved? Brain-related psychiatry is essential for us to know what exactly went wrong with our patients. Curative interventions are impossible before we understand about the etiopathology of our patients. How can we approach this daunting task? It has recently become apparent that global-distributed neuronal-network brain disturbances cause psychiatric disorders. Thus we need to find the correlated underlying neuronal-network disturbances of the various phenomenological manifestations of psychiatric disorders. Hypothesis Neuro Analysis is the proposed approach and Clinical Brain Profiling is a concrete plan by which mental disorders can be translated into their associated brain disturbances. A concise over-view explanation of NeuroAnalysis is presented in this hypothesis. Once we start eliminating mental disorders, we will understand that neuro-scientific psychiatry has been attained. Conclusion We can conclude the obvious questions of ‘Why?’, ‘How?’ and ‘When?’ associated with NeuroAnalysis from this hypothesis as follows: 1. Why?: Because we need to know what went wrong with our patients in order to cure them. 2. How?: We associate psychiatric phenomenology to neuronalnetwork disturbances in the brain. 3. When?: When we cure patients using the insights concisely described heretofore. Introduction If one follows the general literature of neuroscience in psychiatry it is apparent that over the last decade, ‘mental disorders’ have been found to correlate with disturbances to global-distributed brain functions. If in the past, brain functions and disturbances were associated to localised-brain damage, in the recent times, it has become increasingly obvious that multiple parallel brain locations are involved in mental disorders; thus, disturbances to the global network in the brain account for mental illnesses. Recent comprehensive formulations of this type of network approach to mental disorders are described by Menon1 in his article ‘Large-scale brain networks and psychopathology: a unifying triple network model’ and by Joshua Buckholtz and Andreas MeyerLindenberg2 in ‘Psychopathology and the human connectome: toward a transdiagnostic model of risk for mental illness’. ‘Connectome’ is a new emerging concept that defines largescale whole brain network organisation. Global brain disturbances potentially help to conceptualise higherlevel mental functions and disturbances, as emergent properties. Single neurons, genes or neurotransmitters, do not possess properties such as ‘awareness’, ‘mood’ or ‘personality’, but whole brain organisation emerges to support such phenomena. They are ‘emergent properties’, because they emerge from the brain functions as a whole. Despite this, still there is a challenge of associating mental disorders to their causes at the level of brain disturbances, or in other words the creation of neuroscientific psychiatry. Today, the psychiatric diagnosis is descriptive, patients are classified and treated according to ‘signs’ and ‘symptoms’, and at the taxonomic level, the Diagnostic and Statistical Manual of Mental Disorders (DSM) diagnostic nosology is not brainrelated. Unlike other fields of medicine where the nosology reflects the aetiology, for example the diagnosis of ‘appendicitis’ refers to a location in the body, the ‘appendix’ and to the pathology, i.e., the infection; the diagnosis of ‘depression’ is not associated to brain systems or function. Thus, rather than descriptive psychiatry, neuroscientific psychiatry is critical, because only neuroscientific psychiatry will lead us to effective treatments for mental disorders. The identification of the causes of mental disorders is crucial if we aim to cure them. Being said that the first question of the title of this manuscript is answered, ‘Why?’ we need neuroscientific psychiatry, i.e., ‘NeuroAnalysis?’ to cure our patients3. As the title implies, we will explain ‘How?’ we can achieve ‘NeuroAnalytic’ neuroscientific psychiatry. Finally, ‘When?’. When we shall achieve it, or in other words, what are the criteria by which we shall achieve NeuroAnalytic psychiatry. Hypothesis Capitalising on the vast literature of neuroscience combined with Physics M ed ic al E du ca tio n Corresponding author Email: av_peled@netvision.net.il, neuroanalysis @gmail.com Sha’ar Menashe Mental Health Centre, Hadera, Israel Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel

Neuro analysis: a neuro scientific psychiatry. Why? how? and when?