English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Major head and neck surgeries especially in difficult airway patients have a great hazard for post-operative laryngo-pharyngeal oedema and airway obstruction. In this prospective study, mannitol was administrated intra-operatively in an attempt to reduce airway oedema and hence post-extubation airway collapse and obstruction. Materials and methods Two hundred patients undergoing maxillofacial and radical neck surgeries were randomly allocated into the following two equal groups: (1) Group M: in which 0.25 gm /kg mannitol was given after intubation and 30 minutes before the end of surgery. (2) Group C: in which similar volume of the infused mannitol but lactated Ringer was given in the same time points. Cuff-air leak test, flexible fiberoptic laryngoscopic assessment of the upper airway before extubation, post-extubation clinical evaluation of upper airway obstruction and incidence of post-extubation stridor have been conducted to evaluate airway oedema. Results The total mean cuff-leak volume was significantly higher in Group M than in the Group C. The incidence of moderate upper airway lesion was statistically significant lower in mannitol group than in control group. The incidence of post-extubation stridor (after failed cuff-leak test was 4/17 (24%) in the mannitol group and 6/26 (23%) in the control group after passed cuff-leak test it was 2/83 (0.02%) in the mannitol group and 4/74 (.05%) in the control group). Conclusion Pre-emptive use of mannitol in maxillo-facial and radical neck surgeries is effective and nearly side effect free to reduce airway oedema and post-extubation airway obstruction.

Role of preemptive use of mannitol in reducing airway edema following maxillofacial and radical neck surgeries