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Leaves of Ligustrum vulgare are an alternative, sustainable source for oleuropein. Acidic hydrolysis of oleuropein furnishes hydroxytyrosol in good yield. This approach is one of the most convenient ways to access significant amounts of oleuropein as well as of hydroxytyrosol from plant material readily accessible all over the year and throughout Eurasia. Harvesting the leaves in winter doubles the amount of oleuropein that can be extracted from the plant material.

Facile access to oleuropein and hydroxytyrosol from Ligustrum vulgare-a plant material growing all over Eurasia