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In this paper I give a major update of quantum gravity framework project. Theheuristic conceptual framework proposed in previous versions is expanded toinclude structure formation and consciousness in the universe. A Path Integralversion of decoherence in curved space-time is introduced as major update. Thenwe discuss the philosophical insights into structure formation in the universeand consciousness. We introduce various mathematical concepts to describestructure formation in the universe and consciousness.

Quantum Gravity Framework 4.1: Fully Path Integral Framework, Structure Formation and Consciousness in the Universe