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- Rheum tanguticum has long been used in oriental medicine as antipyretics, analgesics, anti-inflam-mation, aperient, hypertension medicine and medicine for skin disease. This study has investigated the effectivenessof defense for gastritis making use of Rheum tanguticum and its similar plants, Rumex cripus , Rheum officinale , Rhempalmatum and Rheum undulatum. Chysophanol, chrysophanol-8-O-glc, Desoxyrhaponticin desoxyrhaponti- genin,emodin, isorhaponticin, 2-methoxy-4-hydroxyanthraquinone-5-O- glc, physcion, pirace-tannol-3'-O-glc, resveratrol,rhaponticin and rhapontigenin are used as the components of Rheum tanguticum. In HCl·ethanol-induced gastritis inrat, the most effective extract was 70 percent ethanol which is of Rheum tanguticum, showing the inhibition of 91.8percent to the gastric lesions. 70% ethanol extract of Rhem palmatum and Rumex cripus shown inhibition of 75.6 per-cent and 73.2 percent, respectively. This effectiveness is considered as acid-neutralizing capacity, anti-H.pylori andanti-oxidant activity. 70% ethanol extract of Rheum tanguticum and its component, piracetannol-3'-O-glc exhibitedhigher free radical scavenging activity than others. These results suggest that Rheum species extracts and their activecomponents could be utilized for the treatment of gastritis. Furthermore, these results are expected to contribute thestandardization with objectivity and reliability for Rheum species, medicinal herbs. In addition, it can contribute to theprevention of indiscriminate distribution of imitation, and the rising rate of dependence on imports of medicinal herbs,and mixing prevention of low-quality goods.Key words : Rheum tanguticum, gastritis, anti-oxidant, H.pylori

A Study on the Antigastritic Effects of Rheum Species Extracts and Their Active Components