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Bi- and multinucleated (B/M) cells are present in a variety of tumors. We evaluated lobular carcinoma in situ (classic and pleomorphic types) and ductal carcinoma in situ (DCIS) to determine if this objective morphologic feature aids the differential diagnosis.

Multinucleation Is an Objective Feature Useful in the Diagnosis of Pleomorphic Lobular Carcinoma In Situ